Course description
The course aims to offer participants an understanding about lineage tracing approaches to map the developmental history of cells within a tissue. This knowledge provides fundamental insights into normal tissue development and diseases such as cancer. We cover most recent methods that allow combined lineage tracing and single-cell transcriptomics for detailed comparisons between molecular and developmental histories.
This course introduces the foundational concepts of various single-cell lineage tracing approaches, covering their experimental implementation, computational analysis, and data interpretation. Featuring renowned international speakers who have made pioneering contributions to method development and biological discovery, the course also provides ample opportunities for students to engage with experts and discuss topics relevant to their own research.
Prerequisites and Selection
Prerequisite courses, or equivalent
No prerequisite courses, or equivalent, demanded for this course.
Selection
Selection will be based on:
1) the relevance of the course syllabus for the applicant’s individual study plan/research (according to written motivation).
2) start date of doctoral studies (priority given to earlier start date).
Course director
Michael Ratz
Course syllabus
C5F6061
Department
Department of Cell and Molecular Biology
Doctoral programme
Cell Biology and Genetics (CBG)
Type of course
**Other course
Keywords
lineage tracing, single-cell rna-seq, development, stem cells, barcoding