Nucleic Acid Chemistry and Therapy

Third-cycle level | 3.0 credits (HEC) | Course code: H5F5737
HT 2025
Study period: 2025-09-15 - 2025-10-03
LANGUAGE OF INSTRUCTION: The course is given in English
Application period: 2025-04-15 - 2025-05-06
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Course description

The purpose of the course is to enable participants to aquire good and up to date knowledge of nucleic acid chemistry and nucleic acid therapy. Nucleic acids of different kinds are the basis of many new therapies for diseases and the underlying knowledge is vital for future developments.

The intention is to increase general knowledge about nucleic acids and how these can undergo different reactions as well as how oligonucleotides are chemically synthesized and modified for therapeutic or other use.

We expect that this will stimulate and inspire the students in their own research whether they work on nucleic acid biology, therapy, analyse nucleic acids or use nucleic acids/oligonucleotides as tools for investigations. It is an intention to increase understanding of nucleic acids, how these molecules work and how they can be used in therapy. In addition, knowledge on how oligonucleotides are synthesized and how these can be modified will enhance the insight and enable the students to improve their use of oligonucleotides as tools or potential therapeutics.

Prerequisites and Selection

Prerequisite courses, or equivalent

No prerequisite courses, or equivalent, demanded for this course. 

Selection

Selection will be based on:  
1) the relevance of the course syllabus for the applicant’s doctoral project (according to written motivation). 
2) start date of doctoral studies (priority given to earlier start date). 

 

Course director

Roger Strömberg

Course syllabus

H5F5737

Department

Department of Laboratory Medicine

Doctoral programme

Development and Regeneration (DevReg)

Type of course

**Other course

Keywords

mRNA, delivery, nucleid acids, RNA, DNA, Therapy, Chemistry, siRNA, Antisense, Crispr

CONTACTRoger Strömberg
0852481024
roger.stromberg@ki.se