Protein Structure, Function and Disease

Third-cycle level | 4.5 credits (HEC) | Course code: H7F6059
HT 2025
Study period: 2025-09-18 - 2025-12-04
LANGUAGE OF INSTRUCTION: The course is given in English
Application period: 2025-04-15 - 2025-05-06
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Course description

The course deals with the molecular properties of proteins concerning their molecular structure and implementation in biology as well as protein misfolding and the relation to neurodegenerative diseases. The course is based on student presentations on current research topics within the field of protein structure and function, followed by discussions with questions from “opponents” (two assigned students) and audience. In addition, written tasks, including practicals of bioinformatics tools, related to chapters in the course book are part of the course. A focus will be on protein structure determination methods, where invited specialist will give overview presentations. 

This year the course will be run together with a one-day symposium on “Human Proteinopathies”, where invited speakers of the conference will participate in the course.

Prerequisites and Selection

Prerequisite courses, or equivalent

Completed Master studies in the field of biochemistry, biotechnology, biomedicine, biophysics, chemical neuroscience or related subjects.

Selection

Selection will be based on:  
1) the relevance of the course syllabus for the applicant’s individual study plan/research (according to written motivation). 
2) start date of doctoral studies (priority given to earlier start date). 

Course director

Axel Abelein, PhD, Docent

Course syllabus

H7F6059

Department

Department of Medicine, Huddinge

Doctoral programme

Neuroscience

Type of course

**Other course

Keywords

Cryo-EM, X-ray, NMR, Protein structure, Protein function, Protein misfolding diseases

CONTACTAxel Abelein

axel.abelein@ki.se