Course description
The purpose of this 1-week course is to enable doctoral students and postdoctoral fellows to obtain in-depth knowledge on new scientific advancements in metabolic-cardiovascular research, with hands-on workshop experience on methodology/techniques of in vitro, ex vivo, in vivo approaches, histology image-scanner core-facility introduction and visiting, as well as biobank data and sequencing data analysis.
Intended learning outcomes
At the end of the course the participant should:
Be able to describe the novel clinical and basic strategies in cardiovascular research, including specific biobank definition and set up approaches, novel in vitro, ex vivo, and in vivo experimental methods.
Be able to design a preliminary study to observe the pathological alterations in cardiovascular diseases, either as a biomarker or therapeutic targets.
Have obtained knowledge on how to practically perform, analyze and interpret in vitro, ex vivo experiments for cardiovascular studies (eg. ISH, transfection, quantitative live-cell assay).
Be able to show a basic understanding of how to analyze the data from Chip-seq, single-cell RNA-seq and RNA-seq data (via analytical assignments on example data).
Requirements and Selection
Prerequisite courses, or equivalent
No prerequisite courses, or equivalent, demanded for this course.
Selection
Selection will be based on:
1) the relevance of the course syllabus for the applicant’s doctoral project (according to written motivation).
2) start date of doctoral studies (priority given to earlier start date).
Postdoctoral scholars are also welcome to register for the course.
Course director
Hong Jin, MD, Ph.D.
Senior research specialist
Division of Vascular Surgery
Department of Molecular Medicine and Surgery
Bioclinicum, Akademiska Stråket 1, J8:20
Karolinska Institutet
17164 Solna Sweden
hong.jin@ki.se
Phone (work) +46-722144491
Phone (mobile) +46-760572577
Zhichao Zhou MD PhD
Associate Professor and PI
Division of Cardiology
Department of Medicine Solna
J8:20, BioClinicum, Cardiology
Karolinska Institutet
17164, Solna, Sweden
Phone: +46720110866
Email: zhichao.zhou@ki.se
Course syllabus
K1F5528
Department
Department of Molecular Medicine and Surgery
Doctoral programme
Cardiovascular Research (CVR)
Type of course
**Other course
Keywords
metabolic, cardiovascular, translational