Course description
Molecular fundaments of epigenetic control under physiological and pathological conditions will be discussed. We will also examine the interplay between epigenetics and the environment and its potential inheritance. Topics to be covered include the role of DNA methylation, histone post-translational modification, and non-coding RNAs in atherosclerosis, ischemic heart disease, inflammation, hypertension, type 2 diabetes, insulin resistance, and other cardiometabolic diseases in mechanisms of current and future treatment. Moreover, the course will include examples of in vitro and animal models for the evaluation of epigenetics as well as examples of clinical studies. Finally, there will be a major practical component where participants will get the opportunity to perform hands-on bench work in the most common techniques regarding epigenetics.
Prerequisites and Selection
Prerequisite courses, or equivalent
Basic knowledge in molecular biology.
Selection
Selection will be based on:
1) the relevance of the course syllabus for the applicant’s individual study plan/research (according to written motivation).
2) start date of doctoral studies (priority given to earlier start date).
Course director
Julia Sanchez Ceinos
Aida Collado Sanchez
Course syllabus
K2F5678
Department
Department of Medicine, Solna
Doctoral programme
Cardiovascular Research (CVR)
Type of course
**Other course
Keywords
Cardiometabolic, Kardiometabolisk, epigenetic, epigenetik