Imaging in Neuroscience: with a Focus on Functional Magnetic Resonance Imaging Methods

Third-cycle level | 1.5 credits (HEC) | Course code: K8F5522
HT 2025
Study period: 2025-10-01 - 2025-11-26
LANGUAGE OF INSTRUCTION: The course is given in English
Application period: 2025-04-15 - 2025-05-06
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Course description

The main purpose of the course is to enable the students to acquire solid understanding of the tools available to analyze brain activity data measured with functional magnetic resonance imaging (fMRI). The students will develop the ability to critically review results provided by different methods, to select the most adequate tools and experimental designs to answer different questions and to compare their relative advantages.

The course focuses on experimental design and analysis of fMRI data. We will briefly introduce the basis of the blood-oxygen-level dependent (BOLD) signal and how it is measured. The image processing steps, before statistical analysis, will be explained. The application of general linear model analysis to fMRI data will be explained, including random effects analysis and correction for multiple comparisons. We will discuss experimental designs for fMRI studies. The study of functional connectivity using fMRI data will be explained. We will also introduce machine learning techniques for analysis of fMRI data. Finally, structural measures of gray and white matter will be introduced as well as other techniques to measure functional and metabolic brain activity non-invasively.

Prerequisites and Selection

Prerequisite courses, or equivalent

Background in cognitive sciences, psychology, medicine, biomedicine, biology, medical imaging, computational biology or any humanistic discipline where neuroimaging is used as an experimental tool.

Selection

Selection will be based on:  
1) the relevance of the course syllabus for the applicant’s individual study plan/research (according to written motivation). 
2) start date of doctoral studies (priority given to earlier start date). 

 

Course director

Rita Almeida

Peter Fransson

Course syllabus

K8F5522

Department

Department of Clinical Neuroscience

Doctoral programme

Neuroscience

Type of course

**Other course

Keywords

neuroimaging, human brain imaging, fMRI, methods, cognitive neuroscience

CONTACTRita Almeida

rita.almeida@ki.se